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KOKOROMI

Trying new challenges for mental and physical happiness

Thank you for visiting our website. Our goal is to revolutionize mental and physical health by quickly visualizing stress in humans and animals, for example, with our simple biomolecular sensing technology derived from molecular chemistry and semiconductor technology. We invite you to visit our website to learn more about our technology. For further information, please contact us directly.

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Our Profile

KOKOROMI Inc. is a startup company established with the support of the Waseda PoC Fund Program based on biosensor technology developed by the Osaka-Momma Laboratory (Applied Physical Chemistry Division) at Waseda University. Currently, in collaboration with the Momma Laboratory , KOKOROMI is working on the development of cutting-edge molecular sensing technology, while also focusing on researching market needs, user habits and trends in order to provide biosensing that is useful to people.

The company was founded in 2022 with the aim of contributing to the health of humans and animals by providing devices that allow anyone to easily detect biomarkers in their surroundings through integrated biosensing technology using silicon semiconductors. With the cooperation of experts in life science, applied chemistry, electronics and information technology, we are striving to become a leader in developing new biosensing markets.

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Skin patch type sensor (Reference 1)

How biosensors work (Reference 2)

Introducing Technology

KOKOROMI Inc. aims to provide a technology that can repeatedly measure the concentration of specific biomolecules using a biosensor in which proteins or nucleic acids that capture specific biomolecules are immobilized on a semiconductor chip as a uniform molecular film.

For example, biosensors that measure the concentration of specific molecules in saliva or sweat will enable simple checks of immunity at home or in the workplace, and may even help us understand the health and mental health of pets, cows, and other animals.

The photo on the left shows a demonstration of a stick-on sensor that uses nanosheets and was developed to measure the ion concentration in sweat.

We are also working on developing simple testing technologies for various molecular markers that are useful in medicine and health, such as for viruses, food allergens, and blood levels of anti-cancer drugs.

References

Hiroyuki Ohashi, Tetsuya Osaka, "Skin-attachable biosensor", Surface Technology, 74 (1), 43-47 (2023)
Shigeki Kuroiwa, Hiroyuki Ohashi, Tetsuya Osaka, "Development of biosensors using field-effect transistors", Electrochemistry, 88 (4), 317-325 (2020).

Related news

"University and National Research Institute Startups: Social Innovation with Deep Tech (4) Attempt: Development of Sensor for Biomarkers to Rapidly Measure Stress in Living Things," Nikkan Kogyo Shimbun, December 8, 2022, p. 23.
"Simple Stress Test Using Saliva," Nikkei Science, October 2020 issue, Japan Watch, pp. 18-19.

Papers

H. Hayashi, A. Enami, H. Fujita, S. Kuroiwa, K. Ohashi, M. Kuwahara, T. Osaka, T. Momma: "Field-effect transistor biosensor with signal amplification by ternary initiation complexes for detection of wide-range RNA cocentration", Talanta , 273, 125846, 2024.
H. Hayashi, M. Fujita, S. Kuroiwa, K. Ohashi, M. Okada, F. Shibasaki, T. Osaka, T. Momma, "Semiconductor-based biosensor exploiting competitive adsorption with charged pseudo-target molecules for monitoring 5-fluorouracil concentration in human serum", Sensors and Actuators B: Chemical , 134495, 2023.

Introduction Video